Разработана вакцина против covid-19

PATENT DOCUMENTS

Russian patents

  • PATENT DOCUMENTS
    rotavirus vaccine
  • PATENT DOCUMENTS
    vaccine against tuberculosis
  • PATENT DOCUMENTS
    immunostimulatory agent 2
  • PATENT DOCUMENTS
    a vaccine against pneumonia
  • PATENT DOCUMENTS
    flu vaccine
  • PATENT DOCUMENTS
    antitumor agent_syndecazumab 2
  • PATENT DOCUMENTS
    orexin A as an activity modulator
  • PATENT DOCUMENTS
    antitumor agent_leguzumab
  • PATENT DOCUMENTS
    immunostimulatory agent
  • PATENT DOCUMENTS
    antitumor agent_ syndecazumab
  • PATENT DOCUMENTS
    producer of CRM197 adjuvant
  • PATENT DOCUMENTS
    cosmetic
  • PATENT DOCUMENTS
    анальгетик

Eurasian patents

PATENT DOCUMENTS
flu vaccine
PATENT DOCUMENTS
rotavirus vaccine
PATENT DOCUMENTS
interferon gamma producing strain
PATENT DOCUMENTS
vaccine against pneumonia
PATENT DOCUMENTS
vaccine against tuberculosis

European patents

PATENT DOCUMENTS
flu vaccine
PATENT DOCUMENTS
vaccine against pneumonia
PATENT DOCUMENTS
analgesic

The Patents Of China

PATENT DOCUMENTS
flu vaccine
PATENT DOCUMENTS
vaccine against pneumonia

Hong Kong Patents

PATENT DOCUMENTS
flu vaccine
PATENT DOCUMENTS
vacine against pneumonia

Japan Patents

PATENT DOCUMENTS
vaccine against pneumonia

U.S. patents

PATENT DOCUMENTS
vaccine against pneumonia
PATENT DOCUMENTS
flu vaccine

Patents Of Cuba

PATENT DOCUMENTS
vaccine against pneumonia
PATENT DOCUMENTS
flu vaccine

Patents of Mexico

PATENT DOCUMENTS
vaccine against pneumonia

Patents of Ukraine

PATENT DOCUMENTS
flu vaccine
PATENT DOCUMENTS
vaccine against pneumonia

List of published patent documents

  1. Pat. 3219798 Europe, IPC A61K31/7088; A61P25/04; C12N15/09; C12N15/10; C12N15/33. Plasmid DNA, coding for HNP-1, or HNP-2, or HNP-3, bacterial producer, analgesic agent (variants) [Text] / Dukhovlinov I. V., Orlov A. I.; applicants Dukhovlinov I. V., Orlov A. I.; applied on 09.06.17, publ. 17.07.2019; priority 10.11.14, No. 20140145169 (RF) – 24 p.: Il.
  2. Application 20170092364 Eurasia, IPC A61K38/22, A61P25/04, C12N1/21, C12N15/16, C12N15/74. Plasmid DNA encoding beta-endorphin, bacterial producer, analgesic agent [Text] / Dukhovlinov I. V. (RU); / Dukhovlinov I. V. (RU). – No. 20170092364; applied on 26.11.2017; publ. 31.05.2019. – 19 p.: Il.
  3. International application PCTRU2018050128, IPC A61K48/00; C07K14/675; C12N15/16; C12N15/63. Plasmid DNA encoding beta-endorphin, bacterial producer, analgesic agent [Text] / Dukhovlinov I. V.; applicant Dukhovlinov I. V. (RF). – No. WO2019103659; applied on 17.10.2018; publ. 31.05.2019; priority 26.11.2017, No. 20170092364 (EA). – 19 p.: Il.
  4. International application PCTRU2018050142, IPC A61K38/27; A61K38/30; A61P25/28. Method of multiple sclerosis treatment (variants) [Text] / Dukhovlinov I. V.; applicant Dukhovlinov I. V. (RF). – No. WO2019103660; applied on 18.11.2018; publ. 31.05.2019; priority 21.11.2017, No. 20170140515 (RF). – 21 p.: Il.
  5. Application 20170828045 Europe, IPC A61K38/10; a61k38/18; A61K38/40; A61P19/02; C07K14/475; C07K14/79; C07K16/46; C07K19/00; C07K7/08; C12N15/62; C12N15/63. Fusion protein, polynucleotide, genetic construct, producer, preparation for regeneration of cartilage (variants) [Text] / Dukhovlinov I. V., Fedorova E. A; applicant LLC Biochemical Agent. – No. 3484928; applied on 11.02.19; publ. 22.05.19; priority 14.07.16, No. 20160000575 (EA). – 1 p.: Il.
  6. Application 2017140515 Russian Federation, IPC A61K 38/27 (2006.01), A61K 38/30 (2006.01), A61P 25/28 (2006.01). Method of multiple sclerosis treatment (variants) [Text] / Dukhovlinov I.V. (RU) ; applicant Dukhovlinov I. V. (RU). – No. 2017140515; applied on 21.11.2017, publ. 21.05.2009.- 1 p.
  7. Application 201791989 Eurasia, IPC C07K14/61; C12N1/21; C12N15/12; C12N15/70; C12R1/19. Producer strain of somatotropin of predominantly monomeric form [Text] / Dukhovlinov I. V. (RU), Fedorova E. A. (RU); applicant Dukhovlinov I. V. (RU). – No. 201791989; applied on 08.10.2017; publ. 30.04.2019. – 17 p.: Il.
  8. . Pat. 2685957 Russian Federation, IPC C07K14/255; C07K14/315; C07K19/00. Fusion recombinant protein having protective properties against Streptococcus pyogenes [Text] / Suvorov A. N., Dukhovlinov I. V., Leontieva G. F., Grabovskaya K. B., Duplik N. V., Kramskaya T. A., Shevchenko V. Yu., applicant Federal state budgetary scientific institution ” Institute  of experimental medicine” (FGBNU “IEM”) (RU). – No. 2016152455; applied on 28.12.2016, publ. 23.04.2019, Byul. No. 12. – 14 p.
  9. International application PCTRU2018050040, IPC C07K14/61; C12N1/21; C12N15/18; C12N15/63; C12N15/70. Producer strain of somatotropin of predominantly monomeric form [Text] / Dukhovlinov I.V., Fedorova E. A.; applicant Dukhovlinov I. V. (RF). – No. WO2019070162; applied on 12.04.2018; publ. 11.04.2019; priority 08.10.2017, No. 20170091989 (EA). – 15 p.: Il.
  10. Application 20178043652 China, IPC A61K38/10; A61K38/18; A61K38/40; A61P19/02; C07K14/475; C07K14/79; C07K16/46; C07K19/00; C07K7/08; C12N15/62; C12N15/63. Fusion protein, polynucleotide, genetic construct, producer, preparation for regeneration of cartilage (variants) [Text] / Dukhovlinov I. V., Fedorova E. A; applicant LLC Biochemical Agent [RF]. – No. 109563173 ; applied on  14.01.19; publ. 02.04.19; priority 14.07.16, No. 20160000575 (EA). – 23 p.: Il.
  11. Application 201791906 Eurasia, IPC A61K31/711; A61K39/04; A61P31/06; C12N15/31. Vaccine based on a fusion protein and DNA for the prevention and treatment of tuberculosis (variants) [Text] / Dukhovlinov I. V. (RU), Fedorova E. A. (RU); applicants Dukhovlinov I. V. (RU), Fedorova E. A. (RU). – No. 201791906; applied on  24.09.2017; publ. 29.03.2019. – 24 p.: Il.
  12. International application PCTRU2018050117, IPC A61K31/7088; A61K39/04; A61P31/06. Vaccine based on a fusion protein and plasmid DNA [ Text] / Dukhovlinov I. V., Fedorova E. A.; applicants Dukhovlinov I. V. (Russian Federation), E. A. Fedorova (Russia). – No. WO2019059817; applied on  23.09.2018; publ. 28.03.2019; priority 24.09.2017, No. 20170091906 (EA). – 23 p.: Il.
  13. Application 20197004225 Korea, IPC A61K38/10; A61K38/18; A61K38/40; A61P19/02; C07K14/475; C07K14/79; C07K16/46; C07K19/00; C07K7/08; C12N15/62; C12N15/63. Fusion protein, polynucleotide, genetic construct, producer, preparation for regeneration of cartilage (variants) [Text] / Dukhovlinov I. V., Fedorova E. A; applicant LLC Biochemical Agent [RF]. – No. 20190028505 ; applied on  13.02.19; publ. 18.03.19; priority 14.07.16, No. 20160000575 (EA). – 22 p.: Il.
  14. Pat. 031495 Eurasia, IPC A61K 39/04 (2006.01), A61P 31/06(2006.01). Anti-tuberculosis vaccine based on recombinant proteins Ag85B, TB10. 4, FliC [ Text] / Dukhovlinov I. V., Kadykov L. A., Simbirtsev A. S., Fedorova E. A. ; Patentee LLC “Exifarm”. – no. 201600316; applied on  05.05.2016, publ. 31.01.2019, Byul. No. 1, priority 19.03.15, No. 2015109715 (Russian Federation.) – 9 p.
  15. Application 2019002580 USA, IPC C07K16/28. Humanized monoclonal antibody specific to syndecan-1 [Text] / Dukhovlinov I. V., Orlov A. I.; Balazovsky M.; Spector G. M.; applicants Dukhovlinov I. V., Orlov A. I.; Balazovsky M.. – No. 201615745294; applied on 21.07.2016; publ. 03.01.19; priority 20.07.15, No. 20150129656 (RF). – 24 p.: Il.
  16. Pat. 031404 Eurasia, IPC 2006.01 A61K 39/12. Vaccine for prevention and treatment of rotavirus infection containing a fusion protein as an active agent (variants)  [Text] / Dukhovlinov I. V., Kadykov A. L., Simbirtsev A. S.; applicant and Patentee LLC “Exifarm” (RF). – No. 201501001; applied on 30.04.2014, publ. 28.12.2018, Byul. No. 12; priority 15.05.13; No. 2013122473 (RF). – 23 p.
  17. Pat. 2863944 Europe, IPC A61K39/09; A61P31/04; C07K14/315. Fusion protein vaccine against pneumonia caused by streptococcus pneumoniae [Text] / A. N. SUVOROV, DUKHOVLINOV I. V., ORLOV A. I., BAIGUZIN E. J.; applicant and Patentee EPITOPE LTD . – No. 20130806364; applied on 22.01.2014; publ. 19.12.18; priority 22.06.2012, No. 2012126328 (RF). – 14 p.: Il.
  18. Pat. 2672861 Russian Federation, IPC 2006.01 A61K 38/05, A61K 38/21,A61K 47/00, A61K 9/20. Composition based on interferon of type I or III and gamma-D-glutaminyl-L-tryptophan for prevention and treatment of infectious diseases and immunodeficiency states (variants) [Text] / Bezrukova E.V. (RU), Dukhovlinov I.V. (RU), Ishchenko A.M. (RU), Kadykov A.L.( RU), Kolobov A.A. (RU), Petrov A.V. (RU), Simbirtsev A.S. (RU); patent Holder LLC “Exifarm” (RU). – No. 2014144243; applied on  31.10.2014, publ. 20.11.2018, Byul. No. 32. – 19 p.
  19. Application 2018530993 Japan, IPC A61K39/395, A61K48/00, A61P35/00, C07K16/28, C12N15/13. Humanized monoclonal antibody specific to syndecan-1 [Text] / Dukhovlinov I. V., Orlov A. I.; Balazovskiy M.; Spector G. M.; applicants-Dukhovlinov I. V., Orlov A. I.; Balazovskiy M. B.-No. 20180502148; applied on 21.07.2016; publ. 25.10.2018; priority 20.07.15, No. 20150129656 (RF). – 22 p.: Il.
  20. Pat. 1216499 Hong Kong, IPC A61K; A61P; C07K. Polyvalent fusion protein vaccine against influenza [Text] / Dukhovlinov I. V., Orlov A. I., Tsybalova L. M., Kiselev O. I.; applicant and Patentee ABS LTD . – No. 16104349.2; applied on  15.04.16; publ. 14.09.2018; priority 15.02.13; No. 2013107777 (RF). – 1 p.: Il.          
  21. Application 2017104770 Russian Federation, IPC C12N 15/00 (2006.01). A monoclonal antibody specific to the epitope of HIV-1 – P17 protein [ Text] / Dukhovlinov I. V., Bogomolova E. G., Ishchuk S. A., Akhmetshina A. O., Dobrovolskaya O. A., Fedorova E. A., Simbirtsev A. S., applicant Federal state unitary enterprise “State research Institute of especially pure biological products” of the Federal medical and biological Agency (RU). – No. 2017104770; applied on  14.02.2017, publ. 14.08.2018, Byul. No. 23. – 1 p.
  22. Application 201700089 Eurasia, IPC C07C 279/14 (2006.01), C07C 277/08 (2006.01), A61P 9/06 (2006.01), a61p 25/28 (2006.01), A61K 31/155 (2006.01). Phenylcreatin, its application and method of its production / Dukhovlinov Ilya Vladimirovich (RU); applicant Alekseev Alexey Viktorovich. – No. 201700089; applied on  20.01.2017, publ. 31.07.2018. – 22 p.
  23. International application PCTRU2018050004, IPC A61K31/155, A61P25/28, A61P9/06, C07C277/08, C07C279/14 (2006.01). Phenylcreatine, its use and method of its production [Text] / Dukhovlinov I. V.; applicant Alekseev A.V. (RF). – No. WO 2018135977; applied on  18.01.2018; publ. 26.07.2018; priority 20.01.2017, No. 201700089 (EA). – 21 p.: Il.         
  24. Pat. 2956168 Europe, IPC A61K39/00, A61K39/12, A61K39/145, A61K39/295, A61P31/16, C07K19/00, C12N7/00. Polyvalent Fusion Protein Vaccine Against Influenza [Text] / Dukhovlinov I. V., Orlov A. I., Tsybalova L. M., Kiselev O. I.; applicant UBS LTD; Pat.owner UBS LTD . – No. 20140751295; applied on  14.02.14; publ. 25.07.2018; priority 15.02.13, No. 2013107777 A (RF). – 20 p.: Il.
  25. Application 18103246.6 Hong Kong, IPC A61K31/7088; A61P25/04; C12N15/09; C12N15/10; C12N15/33. Plasmid DNA, coding for HNP-1, or HNP-2, OR HNP-3, bacterial producer, analgesic agent (variants) [Text] / DUKHOVLINOV I. V., ORLOV A. I.; applicants DUKHOVLINOV I. V., ORLOV A. I.; No. 1243732; applicants 07.07.2017; publ. 20.07.18; priority 10.11.14, No. 20140145169 (RF). – 26 p.: Il.
  26. Application 2016152819 Russian Federation, IPC C12N 15/09, C07K 14/315, A61K 39/09 (2006.01). Fusion recombinant polypeptides for vaccine production against Streptococcus agalactiae [Text] / Suvorov A. N., Dukhovlinov I. V., Leontieva G. F., Grabovskaya K. B., Kramskaya T. A., Shevchenko V. Yu. / Federal state budgetary scientific institution ” Institute of experimental medicine “(FGBNU” IEM”) (RU). – No. 2016152819; applied on  30.12.2016, publ. 03.07.2018, Byul. No. 19. – 1 p.
  27. Application 2016152455 Russian Federation, IPC C12N 15/00 (2006.01). Fusion recombinant protein having protective properties against Streptococcus pyogenes [Text] / Suvorov A. N., Dukhovlinov I. V., Leontieva G. F., Grabovskaya K. B., Duplik N. V., Kramskaya T. A., Shevchenko V. Yu. / Federal state budgetary scientific institution “Institute of experimental medicine” (FGBNU “IEM”) (RU). – No. 2016152455; applied on  28.12.2016, publ. 02.07.2018, Byul. No. 19. – 1 p.            
  28. Application 1501004605 Thailand. Polyvalent fusion protein vaccine against influenza [Text] / Dukhovlinov I. V., Orlov A. I., Tsybalova L. M., Kiselev O. I.; applicant UBS LTD. – No. 1501004605; applied on  14.08.2015; publ. 21.06.2018; priority 14.02.14, No. 20130107777 (RF). – 1 p.: Il.
  29. Application 108137692 China, IPC C07K16/28; C12N15/13. Humanized monoclonal antibody specific to syndecan-1 [Text] / Dukhovlinov I. V., Orlov A. I.; Balazovsky M.; Spector G. M.; applicants Dukhovlinov I. V., Orlov A. I.; Balazovsky M. B.-No. 2016851714; applicants 21.07.2016; publ. 08.06.2018; priority 20.07.15, No. 20150129656 (RF). – 33 p.: Il.  
  30. Application 2016147721 Russian Federation, IPC C12N 1/00 (2006.01). Escherichia coli BL21 DE3 pColdIII-1269A strain, a method for producing CRM197 protein and vaccine composition based on it [Text] / Simbirtsev A. S., Dukhovlinov I. V., Bogomolova E. G., Dobrovolskaya O. A., Fedorova E. A., Ishchuk S. A., applicant Federal state unitary enterprise “State research Institute of especially pure biological products” of the Federal medical and biological Agency (RU). – No. 2016147721; applied on  06.12.2016, publ. 06.06.2018, Byul. No. 16. – 1 p.             
  31. Application 3325511 Europe, IPC C07K16/28; C12N15/13. Humanized monoclonal antibody specific to syndecan-1 [Text] / Dukhovlinov I. V., Orlov A. I.; Balazovsky M.; Spector G. M.; applicants Dukhovlinov I. V., Orlov A. I.; Balazovsky M., Spector G. M.-No. 20160828139; applied on 21.07.2016; publ. 30.05.2018; priority 20.07.15, No. 20150129656 (RF). – 1 p.
  32. Application 2016145253 of the Russian Federation, IPC C12N 1/00 (2006.01). Fusion protein, synthetic DNA encoding the specified protein, expression vector, producer strain of synthetic DNA and method of obtaining plasmid DNA [Text] / Dukhovlinov I. V.., applicant LLC “Exifarm” (EN). – No. 2016145253; applied on  18.12.2016, publ. 20.05.2018, Byul. No. 14. – 3 p.
  33. Pat. 355642 Mexico, the IPC A61K39/09; A61P31/04; C07K14/315. Fusion protein vaccine against pneumonia caused by Streptococcus pneumoniae [Text] / Suvorov A. N., Dukhovlinov I. V., Orlov A. I., Baiguzin E. Y.; / EPITOPE LTD. – No. 2014016049; applied on  17.08.15; publ. 25.04.18; priority 22.06.12, № 2012126328 (RF) – 21 p.: Il.
  34. Pat. 116634 Ukraine, IPC A61K39/09; A61K39/112; C07K14/315; C12N15/63; A61P31/04; C07K19/00. Vaccine against pneumonia caused by Streptococcus pneumoniae, based on a fusion protein [Text] / Suvorov A. N., Dukhovlinov I. V., Orlov A. I., Baiguzin E. Ya.; patentee LLC “Epitope” (Russia).  – No. 20150000499; applied on  21.06.2013; publ. 25.04.2018; priority priority 22.06.2012, № 2012126328 (RF). – 16 p.: Il.  
  35. Application 112017009607 2 Brazil, IPC A61K31/7088; A61P25/04; C12N15/09; C12N15/10; C12N15/33. Plasmid DNA coding for HNP-1, or HNP-2, or HNP-3, bacterial producer, analgesic agent (variants) / DUKHOVLINOV I.V. [RF]; ORLOV A.I. [RF]; applicants DUKHOVLINOV I.V. [RF]; ORLOV A.I. [RF]. – applied on 10.11.2015, publ. 03.04.2018, priority 10.11.2014, No. 2014014516 (RF).           
  36. Pat. 2649132 Russian Federation, IPC A61K 39/15 (2006.01). A method for obtaining the active agent of a vaccine against rotavirus infection: FliCVP6VP8 / Bogomolova E.G. (RU), Dukhovlinov l.V. (RU), Dobrovolskaya O.A. (RU), Fedorova E.A. (RU), Ishchuk S.A. (RU), Simbirtsev A.S. (RU); applicant and patentee Federal state unitary enterprise “State research Institute of especially pure biological products” of the Federal medical and biological Agency (RU). – No. 2017127940; applied on  03.08.2017, publ. 29.03.2018, Byul. No. 10. – 13 p.           
  37. Pat. 2647771 Russian Federation, IPC C07K 14/575 (2006.01), A61K 38/22 (2006.01), C12N 15/70 (2006.01), C12N 1/21 (2006.01), C12P 21/02 (2006.01), C12R 1/19 (2006.01) . Method for producing recombinant human orexin a, plasmid DNA, producer strain / Dukhovlinov l.V. (RU), Orlov A.I. (RU), Fedorova E.A. (RU), Korneva E.A. (RU), Derevtsova K.Z. (RU), Novikova N.S. (RU), Perekrest S.V. (RU); applicant and Patentee limited liability Company “Orexal” (Orexal LLC) (RU). – No. 2016116370; applied on  26.04.2016, publ. 19.03.2018, Byul. No. 8. – 12 p.      
  38. Pat. 2647831 Russian Federation, IPC A61K 39/04 (2006.01), A61K 39/39 (2006.01), A61P 31/06. Vaccine against tuberculosis / Simbirtsev A.S. (RU), Dukhovlinov I.V. (RU), Dobrovolskaya O.A. (RU), Fedorova E.A. (RU); applicant and patentee Federal state unitary enterprise “State research Institute of especially pure biological products” of the Federal medical and biological Agency (RU). – No. 2017108682; applied on  15.03.2017, publ. 19.03.2018, Byul. No. 8. – 8 p.              
  39. Application 2018057837 USA, IPC A61K38/17, C07K14/47, C12N15/85. Plasmid DNA, coding for HNP-1, or HNP-2, or HNP-3, bacterial producer, analgesic agent (variants) [Text] / Dukhovlinov I. V., Orlov A. I.; applicants Dukhovlinov I. V., Orlov A. I.; applied on 10.11.15, publ. 01.03.2018; priority 10.11.14, No. 20140145169 (RF) – 18 p.: Il.              
  40. Application 201600575 Eurasia, IPC C07K 19/00 (2006.01), C07K 7/08 (2006.01), C07K 14/475 (2006.01), C07K 14/79 (2006.01), C07K 16/46 (2006.01), C12N 15/62 (2006.01), C12N 15/63 (2006.01), A61K 38/10 (2006.01), A61K 38/18 (2006.01), A61K 38/40 (2006.01), A61P 19/02 (2006.01). Fusion protein, polynucleotide, genetic design, producer, preparation for cartilage regeneration (variants) / Dukhovlinov I.V.(RU), Fedorova E.A. (RU); applicant Limited Liability Company “Biochemical Agent”. – No. 201600575; applied on  2016.07.14, publ. 2018.01.31. – 41 p.                                        
  41. Pat. 104994871 China, IPC A61K39/145, A61K39/295, A61P31/16, C07K19/00. Polyvalent fusion protein vaccine against influenza [Text] / Dukhovlinov I. V., Orlov A. I., Tsybalova L. M., Kiselev O. I.; applicant and patentee UBS LTD . – No. 2014808848; applied on  14.08.15; publ. 26.01.2018; priority 15.02.13; No. 2013107777 (RF). – 20 p.: Il.            
  42. International application PCT/RU2017/000521, IPC C07K 19/00 (2006.01), C07K 7/08 (2006.01), C07K 14/475 (2006.01), C07K 14/79 (2006.01), C07K 16/46 (2006.01), C12N 15/62 (2006.01), C12N 15/63 (2006.01), A61K 38/10 (2006.01), A61K 38/18 (2006.01), A61K 38/40 (2006.01), A61P 19/02 (2006.01). Fusion protein, polynucleotide, genetic construct, producer, preparation for cartilage regeneration (variants) [Text] / Dukhovlinov I. V., Fedorova E. A.; applicant Limited Liability Company Biochemical Agent (RF). – No. WO 2018/013013; applied on  13.07.2017; publ. 18.01.2018; priority 14.07.2016, No. 201600575 (EA). – 38 p.: Il.
  43. Pat. 115895 Ukraine, IPC A61K 39/295, A61K 39/145, C07K 19/00, A61P 31/16, C12N 7/00, A61K 39/12. POLIVALENTNA VACCINE PROTI GRIPU on OSNOVI GIBRIDNOGO BILKA [Text] / Dukhovlinov I. V., Orlov A. I., Tsybalova L. M., Kiselev O. I.; Patentee UBS LTD (RF). – No. 201508723; applied on  14.02.2014; publ. 10.01.2018, Byul. No. 1; priority 15.02.13; No. 2013107777 (RF). – 16 p.: Il.
  44. Pat. 104470538 China, IPC A61K39/09; A61K39/112; A61P31/04; C07K19/00; C12N15/63. Fusion protein vaccine against pneumonia caused by Streptococcus pneumoniae [Text] / Suvorov A. N., Dukhovlinov I. V., Orlov A. I., Baiguzin E. Y.; applicant EPITOPE LTD [RF]. – No. 20138037745; applied on  15.01.15; publ. 22.12.17; priority 22.06.12, No. 2012126328 (RF). – 14 p.: Il.
  45. Pat. 24288 Cuba, MPC A61C 39/295, A61C 39/145. Polyvalent fusion protein vaccine against influenza [Text] / Dukhovlinov I. V., Orlov A. I., Tsybalova L. M., Kiselev O. I.; applicant and patentee UBS LTD . – No. 20150083; applied on  13.08.15; publ. 08.12.17; priority 15.02.13; No. 2013107777 (RF). – 26 p.: Il.
  46. Application 2017535288 Japan, IPC A61K31/713, A61K48/00, A61P25/04, C12N1/21, C12N15/09. Plasmid DNA, coding for HNP-1, or HNP-2, or HNP-3, bacterial producer, analgesic agent (variants) [Text] / Dukhovlinov I. V., Orlov A. I.; applicants Dukhovlinov I. V., Orlov A. I.; applied 09.05.17, publ. 30.11.17; priority 10.11.14, No. 20140145169 (RF) – 31 p.: Il.
  47. Application 2016116370 Russian Federation, IPC C07K 14/575, A61K 38/22, C12N 15/70, C12N 1/21, C12P 21/02, C12R 1/19 . Preparation on the basis of recombinant human orexin A, method of its production, plasmid DNA, producer strain [Text] / Dukhovlinov I. V., Orlov A. I., Fedorova E. A., Korneva E. A., Derevtsova K. Z., Novikova N. S., Perekrest S. V.; applicant LLC “Orexal” – № 2016116370; application. 26.04.2016; publ. 31.10.2017, Byul. No. 31. – 1 s.
  48. Application 201790929 Eurasia, IPC C12N 15/09, C12N 15/33, C12N 15/10, A61K 31/7088, A61P 25/04. Plasmid DNA encoding HNP-1, or HNP-2, or HNP-3, bacterial producer, analgesic agent (variants) [Text] / Dukhovlinov I. V., Orlov A. I.; applicants Dukhovlinov I. V., Orlov A. I., No. 201790929 ; applied on 10.11.2015; publ. 29.09.2017, priority 10.11.2014, No. 2014145169 (RF). – 38 p.: Il.
  49. Pat. 027981 Eurasia, IPC A61K 39/09, A61K 39/112, C07K 19/00, C12N 15/63, A61P 31/04. Vaccine against pneumonia caused by Streptococcus pneumoniae, based on a fusion protein [Text] / Suvorov A. N., Dukhovlinov I. V., Orlov A. I., Baiguzin E. V.; applicant and Patentee EPITOP LTD.. – No. 201590078; applied on  21.06.13; publ. 29.09.17, Byul. No. 2017-09; priority 22.06.12; No. 2012126328 (RF). – 10 p.: Il.        
  50. Application 2015872724 China, IPC A61K31/7088; A61P25/04; C12N15/09; C12N15/10; C12N15/33. Plasmid DNA, encoding HNP-1, or HNP-2, or HNP-3, bacterial producer, analgesic agent (variants) [Text] / Dukhovlinov I. V., Orlov A. I.; applicants Dukhovlinov I. V., Orlov A. I.; no. CN107208087; applied 07.07.2017; publ. 26.09.17; priority 10.11.14, No. 20140145169 (RF). – 26 p.: Il.    
  51. Pat. 6195089 Japan, IPC A61K39/09, A61P31/00, A61P31/04, C07K14/255, C07K14/315, C07K19/00. Fusion protein vaccine against pneumonia caused by Streptococcus pneumoniae [Text] / Suvorov A. N., Dukhovlinov I. V., Orlov A. I., Baiguzin J. E. ; applicant and Patentee Epitope LTD . – No. 2015-518363; applied on  12.12.14; publ. 20.09.17; priority 22.06.2012, No. 2012126328 (RF). – 15 p.: Il.
  52. Application 20141132135 Brazil, IPC A61K39/09, A61K39/112, A61P31/04, C07K19/00, C12N7/00. Fusion protein vaccine against pneumonia caused by Streptococcus pneumoniae [Text] / Suvorov A. N., Dukhovlinov I. V., Orlov A. I., Baiguzin E. J.; applicant and Patentee Epitope LTD . – No. 112014032135; applied on  19.12.14; publ. 01.08.17; priority 22.06.2012, No. 2012126328 (RF). – 1 p.: Il.
  53. Pat. 027463 Eurasia, IPC A61K 39/295, A61K 39/145, C07K 19/00, A61P 31/16. Polyvalent vaccine against influenza based on fusion protein [Text] / Dukhovlinov I. V., Orlov A. I., Tsybalova L. M., Kiselev O. I.; applicant and patentee UBS LTD. – No. 201500770; applied on  14.02.14; publ. 31.07.17, Byul. No. 7; priority 15.02.13; No. 2013107777 (RF). – 15 p.: Il.     
  54. Application 20177015883 Korea, IPC A61K38/17; A61K48/00; C12N15/85. Plasmid DNA coding for HNP-1 or HNP-2 or HNP-3, bacterial producer, analgesic agent (variants) [Text] / Dukhovlinov I. V.; Orlov A. I.; applicants Dukhovlinov I. V.; Orlov A. I.-No. 20170077252; applicants 10.11.2015; publ. 05.07.2017, priority 10.11.2014, No. 2014145169 (RF). – 25 p.: Il.
  55. Pat. 2624482 Russian Federation, IPC A61K38/16; A61P25/32. Antialcoholic agent [Text] / Dukhovlinov I. V., Korneva E. A., Orlov A. I., Shabanov P. D.; applicant and Patentee FGBNU “IEM”. – No. 2015148672; applied on  12.11.2015; publ. 04.07.2017, Byul. No. 19. – 8 p.: Il.
  56. Application 2015148672 Russian Federation, IPC A61K 38/16, A61P 25/32. Antialcoholic Agent [Text] / Dukhovlinov I. V., Korneva E. A., Orlov A. I., Shabanov P. D.; applicant FGBNU “IEM”. – No. 2015148672; applied on  12.11.2015; publ. 15.05.17, Byul. No. 14. – 1 p.: Il.
  57. Application 2015148298 Russian Federation, IPC C12N 15/00. Producer strain of plasmid DNA encoding HNP-1 or HNP-2 or HNP-3, based on E. coli DH10B/R cells [Text] / Dukhovlinov I. V., Al-Shehadat R. I.; applicants Dukhovlinov I. V. , Al-Shehadat R. I. – No. 2015148298 ; applied 10.11.2015; publ. 11.05.2017, Byul. No. 14. – 1 s.       
  58. Pat. 2615440 Russian Federation, IPC C07K 14/35. Fusion protein, DNA, genetic design, recombinant cell, vaccine based on fusion protein for prevention and treatment of tuberculosis (variants) [Text] / Dukhovlinov I. V., Orlov A. I., Fedorova E. A., Chernyaeva E. N. ; applicants and Pat.owners Dukhovlinov I. V., Orlov A. I., Fedorova E. A., Chernyaeva E. N.-No. 2015119607; applied on  25.05.15; publ. 04.04.17, Byul. No. 10. – 22 p.: Il.
  59. Pat. 2611685 Russian Federation, IPC C07K 16/28, C12N 15/13. Humanized monoclonal antibody specific to syndecan-1 [Text] / Dukhovlinov I. V., Orlov A. I., Balazovsky M. B., Spector D. M.; applicants and Pat.owners Dukhovlinov I. V., Orlov A. I., Balazovsky M. B., Spector D. M. . – No. 2015129656; applied on  20.07.15; publ. 28.02.17, Byul. No. 7. – 26 p.: Il.
  60. Pat. 24238 Cuba, IPC A61K39/09. Fusion protein vaccine against pneumonia caused by Streptococcus pneumoniae [Text] / Suvorov A. N., Dukhovlinov I. V., Orlov A. I., Baiguzin J. E. ; applicant and Patentee Epitope LTD . – No. 2014-0145; applied on  22.12.14; publ. 02.02.17, Byul. No. 01/001; priority 22.06.2012, No. 2012126328 (RF). – 23 p.: Il.        
  61. International application PCT/RU2016 / 000467, IPC C07K 16/28, C12N 15/13. Humanized monoclonal antibody specific to syndecan-1 [Text] / DUKHOVLINOV I. V., ORLOV A. I., BALAZOVSKY M. B., SPEKTOR G. M. (USA) ; applicants DUKHOVLINOV I. V., ORLOV A. I., BALAZOVSKY M. B., SPEKTOR G. M. . – No. WO2017014679; applied on  21.07.16; publ. 26.01.17, priority 20.07.15, No. 2015129656 (RF). – 24 p.: Il.  
  62. Application 2015129656 Russian Federation, IPC S07K 16/28. Humanized monoclonal antibody specific to syndecan-1 [Text] / Dukhovlinov I. V., Orlov A. I., Balazovsky M. B., Spector D. M.; applicants Dukhovlinov I. V., Orlov A. I., Balazovsky M. B., Spector D. M. – No. 2015129656 ; applied on 20.07.15; publ. 23.01.17, Byul. No. 3. – 1 s.              
  63. Application 20160104349 Hong Kong, IPC A61K; A61P; C07K. POLYVALENT FUSION PROTEIN VACCINE AGAINST INFLUENZA [Text] / DUKHOVLINOV I. V., ORLOV A. I., TSYBALOVA L. M., KISELEV O. I. ; applicant UBS LTD . – No. 20160104349; applied on  15.04.16; publ. 18.11.16; priority 15.02.13; No. 2013107777 (RF). – 31 p.: Il.
  64. Pat. 9480737 USA, IPC A61K2039/55516, A61K2039/70, A61K39/145, C12N7/00, A61K39/12, C12N2760/16134, C12N2760/16234. Polyvalent Fusion Protein Vaccine Against Influenza [Text] / Dukhovlinov I. V., Orlov A. I., Tsybalova L. M., Kiselev O. I.; applied on  14.02.14; publ. 01.11.16; priority 15.02.13.  No. 2013107777 (RF). – 14 p.: Il.
  65. Application 201600316 Eurasia, IPC A61K 39/00. ANTITUBERCULOSIS VACCINE BASED on RECOMBINANT PROTEINS Ag85B, TB10. 4, FLiC [ Text] / Dukhovlinov I. V., Kadykov A. L., Simbirtsev A. S., Fedorova E. A.; applicant limited LIABILITY COMPANY “RD-BIOTECH” [RF]. – No. 201600316; applied on  2016.05.05, publ. 2016.10.31, priority 2015.03.19, No. 2015109715 (RF). – 17 p.
  66. Application 201600347 Eurasia, IPC A61K 39/00. Fusion protein, DNA, genetic design, producer, vaccine based on fusion protein for prevention and treatment of tuberculosis (variants) [Text] / Dukhovlinov I. V., Orlov A. I., Fedorova E. A., Chernyaeva E. N.; applicants Dukhovlinov I. V., Orlov A. I., Fedorova E. A., Chernyaeva E. N. . – No. 201600347; applied on  24.05.16; publ. 30.09.16; priority 25.05.15, No. 2015119607 (RF). – 33 p.: Il.
  67. Pat. 2597789 Russian Federation, IPC A61K 31/711, a61r 29/00. ANALGESIC AGENT BASED on PLASMID DNA ENCODING HNP-1 OR HNP-2 OR HNP-3 (VARIANTS) [Text] / Dukhovlinov I. V., Orlov A. I.; applicants and Pat.owners Dukhovlinov I. V., Orlov A. I.-No. 2014145169; applied on  10.11.14; publ. 20.09.16, Byul. No. 26. – 32 p.: Il.
  68. Application 14751295.8 Europe, IPC A61K39/00; A61K39/12; A61K39/145; A61K39/295; A61P31/16; C07K19/00; C12N7/00. POLYVALENT FUSION PROTEIN VACCINE AGAINST INFLUENZA [Text] / DUKHOVLINOV I. V., ORLOV A. I., TSYBALOVA L. M., KISELEV O. I.; applicant UBS LTD. – No. 2956168; applied on  27.08.15; publ. 14.09.16; priority 15.02.13; No. 2013107777 (RF). – 1 p.: Il.      
  69. Application 20150083 Cuba, IPC 2006.01 A61C 39/295. POLYVALENT FUSION PROTEIN VACCINE AGAINST INFLUENZA [Text] / DUKHOVLINOV I. V., ORLOV A. I., TSYBALOVA L. M., KISELEV O. I.; applicant UBS LTD . – No. 20150083; applied on  13.08.15; publ. 29.07.16; priority 15.02.13; No. 2013107777 (RF). – 28 p.: Il.
  70. Application 2014144243 Russian Federation, IPC 2006.01 A61K 38/00, B82B 3/00. Composition based on interferon type I or III and gamma-D-glutaminyl-L-tryptophan for the prevention and treatment of infectious diseases and immunodeficiency states (variants) / Bezrukova E.V. (RU), Dukhovlinov I.V. (RU), Ishchenko A.M. (RU), Kadykov A.L.( RU), Kolobov A.A. (RU), Petrov A.V. (RU), Simbirtsev A.S. (RU); applicant LLC RD-BIOTECH (RU). – No. 2014144243; applied on  31.10.2014, publ. 27.05.2016, Byul. No. 15. – 3 s.          
  71. Application 2014145169 Russian Federation, IPC 2006.01 A61K 31/711, a61r 29/00. Analgesic agent based on plasmid DNA encoding HNP-1, or HNP-2, or HNP-3 (VARIANTS) [Text] / Dukhovlinov I. V., Orlov A. I.; applicants Dukhovlinov I. V., Orlov A. I. – № 2014145169 ; applied on 10.11.14; publ. 27.05.16, Byul. No. 15. – 2 s.
  72. Pat. 9345757 USA, IPC A61K39/09; C07K14/315; A61K39/00. FUSION PROTEIN VACCINE AGAINST PNEUMONIA CAUSED BY STREPTOCOCCUS PNEUMONIAE [Text] / SUVOROV A. N., DUKHOVLINOV I. V., ORLOV A. I., BAIGUZIN E. J.; applicant and Patent holder EPITOPE LTD . – No. 201414579279; applied on  22.12.2014; publ. 24.05.16; priority 22.06.2012, No. 2012126328 (RF). – 10 p.: Il.
  73. International application PCT/RU2015 / 000756, IPC C12N 15/09. PLASMID DNA CODING for HNP-1, or HNP-2, OR HNP-3, BACTERIAL PRODUCER, ANALGESIC AGENT (VARIANTS) [Text] / DUKHOVLINOV I. V., ORLOV A. I., applicants DUKHOVLINOV I. V., ORLOV A. I.-no. WO2016076761; applied on 10.11.15; publ. 19.05.16, priority 10.11.14, No. 2014145169 (RF). – 38 p.: Il.          
  74. Application 201501001 Eurasia, IPC A61K 39/12. Vaccine for the prevention and treatment of rotavirus infection, containing a fusion protein as an active agent (variants) / Dukhovlinov Ilya Vladimirovich (RU), Kadykov Alexander Leonidovich (RU), Simbirtsev Andrey Semenovich (RU); applicant LLC “RD-BIOTECH” (Russia). – No. 201501001; applied on  30.04.2014, publ. 29.04.2016, Byul.  No. 21604. – 1 s.              
  75. Pat. 1208632 Hong Kong, IPC A61K, a61p, C07K, C12N. Fusion protein vaccine against pneumonia caused by Streptococcus pneumoniae [Text] / Suvorov A. N., Dukhovlinov I. V., Orlov A. I, Baiguzin E. J. ; applied on  25.09.15; publ. 11.03.16; priority 22.06.2012, No. 2012126328 (RF). – 10 p.: Il.
  76. Pat. 2575621 Russian Federation, IPC C12N 16/28 (2006.01). Producer strain of methionine-not containing CRM197 on the basis of E. coli BL21 (DE3) cells / Dukhovlinov Ilya Vladimirovich (RU),  Kadykov Alexander Leonidovich (RU), Simbirtsev Andrey Semenovich (RU); applicant and Patentee LLC “RD-biotech” (RU). – No. 2015100909; applied on  13.01.2015, publ. 20.02.2016, Byul. No. 5. – 13 p.
  77. Pat. 2574203, Russian Federation. IPC C07K 16/00. Humanized monoclonal antibody specific to legumain [Text] / Dukhovlinov I. V., Orlov A. I.; patentee UBS LTD; claimed 16.12.13; publ. 10.02.16, Byul.  No. 4. – 29 p.
  78. Application 20150374814 USA, IPC A61K39/145, A61K2039/70, C12N7/00, C12N2760/16234. Polyvalent fusion protein vaccine against influenza [Text] / Dukhovlinov I. V., Orlov A. I., Tsybalova L. M., Kiselev O. I.; applicant and patent holder UBS LTD; applied on 14.02.14, publ. 31.12.15; priority 15.02.13, No. 2013107777 (RF) – 14 p.: Il.             
  79. Application 201500770 Eurasia, IPC A61K 39/295, A61K 39/145, C07K 19/00, A61P 31/16. Polyvalent vaccine against influenza based on fusion protein [Text] / Dukhovlinov I. V., Orlov A. I., Tsybalova L. M., Kiselev O. I.; applicant UBS LTD. – No. 201500770; applied on  14.02.14; publ. 30.12.15, Byul. No. 12; priority 15.02.13; No. 2013107777 (RF). – 27 p.: Il.     
  80. Application 2956168 Europe, IPC A61K39/00, A61K39/12, A61K39/145, A61K39/295, A61P31/16, C07K19/00, C12N7/00. Polyvalent Fusion Protein Vaccine Against Influenza [Text] / DUKHOVLINOV I. V., ORLOV A. I., TSYBALOVA L. M., KISELEV O. I.; applicant and Pat.owner UBS LTD; applied on  14.02.14; publ. 23.12.15; priority 15.02.13, No. 2013107777 A (RF). – 14 p.: Il.
  81. Application 2015010623 Mexico, IPC A61K39/145; A61K39/295; A61P31/16; C07K19/00. POLYVALENT FUSION PROTEIN VACCINE AGAINST INFLUENZA [Text] / DUKHOVLINOV I. V., ORLOV A. I., TSYBALOVA L. M., KISELEV O. I.; applicant UBS LTD . – No. 2015010623; applied on  17.08.15; publ. 15.12.15; priority 15.02.13; No. 2013107777 (RF). – 30 p.: Il.
  82. Application 2015119607 Russian Federation. IPC C12P 21/06. Fusion protein, DNA, genetic design, producer, vaccine based on fusion protein for the prevention and treatment of tuberculosis (variants) [Text] / Dukhovlinov I. V., Orlov A. I., Fedorova E. A., Chernyaeva E. N.; applicants Dukhovlinov I. V., Orlov A. I., Fedorova E. A., Chernyaeva E. N. – № 2015119607; applied on 25.05.15; publ. 27.10.15, Byul. No. 30. – 1 s.
  83. Application 104994871 China, IPC A61K39/12, A61K39/145, C12N7/00. Polyvalent fusion protein vaccine against influenza [Text] / DUKHOVLINOV I. V., ORLOV A. I., TSYBALOVA L. M., KISELEV O. I.; applicant UBS LTD; No. CN104994871; applied on 14.02.14; publ. 21.10.15; priority 14.02.14, No. WO2014RU00096 (international). – 20 p.: Il.
  84. Pat. 2564114 Russian Federation, IPC A61K 31/205, A61P 37/04.  Inducer of IL-12 and IL-1A [Text] / Orlov A. I., Shabanov P. D., Dukhovlinov I. V.; Patentee LLC “Pharmatrix”; applied on 22.05.14; publ. 27.09.15, Byul.  No. 27 . – 16 p.: Il.           
  85. Application 2015109715 Russian Federation, IPC A61K 39/00. Antituberculosis vaccine based on recombinant proteins Ag85B, TB10. 4, FliC [ Text] / Dukhovlinov I. V., Kadykov A. L., Simbirtsev A. S., Fedorova E. A.; applicant LLC “RD-biotech”. – No. 2015109715; applied on  19.03.2015, publ. 20.08.2015, Byul. No. 23. – 1 s.
  86. Application 1000091683 Japan, IPC 2006.01 A61K 39/02. Fusion protein vaccine against pneumonia caused by Streptococcus pneumoniae [Text] / SUVOROV A. N., DUKHOVLINOV I. V., ORLOV A. I., BAIGUZIN E. Y.; applicant EPITOPE LTD [RF]. – No. 2015521618; applied on  12.12.14; publ. 30.07.15; priority 22.06.12, No. 2012126328 (RF). – 18 p.: Il.
  87. Pat. 2557894 Russian Federation, IPC A61K8/33; A61K8/36; A61K8/44; A61K8/67. Cosmetic product for rapid skin recovery / Dukhovlinov I. V., Rezyapkin A. A., Golyshev P. I.; applicant and patentee LLC “Pharma Gen” (Russia). – No. 2013146705; applied on  18.10.2013, publ. 27.07.2015, Byul. No. 21. – 11 p.          
  88. Application 2014016049 Mexico, IPC A61K39/09, A61K39/112, C07K19/00. Fusion protein vaccine against pneumonia caused by Streptococcus pneumoniae [Text] / SUVOROV A. N., DUKHOVLINOV I. V., ORLOV A. I., BAIGUZIN E. Y.; / EPITOPE LTD. – No. 2014016049; applied on  19.12.14; publ. 06.07.15; priority 22.06.12, № 2012126328 (RF) – 21 p.: Il.
  89. Application 201590078 Eurasia, IPC 2006.01 A61K 39/02. Vaccine against pneumonia caused by Streptococcus pneumoniae, based on a fusion protein [Text] / Suvorov A. N., Dukhovlinov I. V., Orlov A. I., Baiguzin E. Ya.; applicant LLC “Epitop” [RF]. – No. 201590078; applied on  22.01.15; publ. 30.06.15; priority 22.06.2012, No. 2012126328 (RF). – 21 p.: Il.
  90. Application 2013155843 Russian Federation, IPC C07K 16/00. Humanized monoclonal antibody specific to legumain [Text] / Dukhovlinov I. V., Orlov A. I.; applicant UBS LTD; applied on  16.12.2013; publ. 27.06.2015, Byul.  No. 1. – 32 p.: Il.
  91. International application PCT/RU2014/000947, IPC C07K 16/28, C07K 16/32, C07K 16/40, C12N 9/50. HUMANIZED MONOCLONAL ANTIBODY SPECIFIC TO LEGUMAIN [Text] / Dukhovlinov I. V. Orlov, A. I. ; applicant UBS LTD. – No. WO2015094018, applied on  15.12.14; publ. 25.06.15; priority 16.12.2013, No. 2013155843 (RF). – 31 p.: Il.
  92. Pat. 2551235 Russian Federation. IPC C07K 16/28. Humanized monoclonal antibody specific to syndecan-1 [Text] / Dukhovlinov I. V., Orlov A. I., Balazovskiy M. B., Spector D. M.; Pat.owners Dukhovlinov I. V., Orlov A. I., Balazovskiy M. B., Spector D. M.; applied on  26.08.13; publ. 20.05.15, Byul.  No. 14. – 20 p.: Il.
  93. Application 2014-145 Cuba, IPC 2006.01 A61K 39/02. Fusion protein vaccine against pneumonia caused by Streptococcus pneumoniae [Text] / SUVOROV A. N., DUKHOVLINOV I. V., ORLOV A. I., BAIGUZIN E. Y.; applicant EPITOPE LTD [RF]. – No. 20140145; applied on  22.12.14, publ. 29.04.15, priority 22.06.12, № 2012126328 (RF). – 24 p.: Il.
  94. Application 14579279 USA, IPC 2006.01 A61K 39/02. Fusion protein vaccine against pneumonia caused by Streptococcus pneumoniae [Text] / SUVOROV A. N., DUKHOVLINOV I. V., ORLOV A. I., BAIGUZIN E. Y.; applicant EPITOPE LTD [RF]. – No. 2015174230; applied on  22.12.14; publ. 29.04.15; priority 22.06.12, No. 2012126328 (RF). – 24 p.: Il.
  95. Application 13806364 Europe, IPC 2006.01 A61K 39/02. Fusion protein vaccine against pneumonia caused by Streptococcus pneumoniae [Text] / SUVOROV A. N., DUKHOVLINOV I. V., ORLOV A. I., BAIGUZIN E. Y.; / EPITOPE LTD. – No. 2863944; applied on  22.01.15; publ. 29.04.15; priority 22.06.12, No. 2012126328 (RF). – 18 p.: Il.
  96. Application 2013146705 Russian Federation. IPC A61K8/33; A61K8/36; A61K8/44; A61K8/67. Cosmetic product for rapid skin recovery [Text] / Dukhovlinov I. V., Rezyapkin A. A., Golyshev P. I. – № 2013146705 ; applied on 18.10.2013; publ. 27.04.2015, Byul.  No. 12 . – 11 p.
  97. International application PCT/RU2014 / 000776, IPC A61K 8/33, A61K 8/36, A61K 8/44, A61K 8/67, A61Q 17/00. COSMETIC FOR RAPID SKIN REGENERATION / Dukhovlinov I. V., Rezyapkin A. A., Golyshev P. I.; applicant LLC “PHARMA GEN” (RF). – No. WO2015057110; applied on  15.10.2014, publ. 23.04.2015, priority 18.10.2013, № 2013146705 (RF). – 14 p.
  98. Application 2015-7001672 Korea, IPC 2006.01 A61K 39/02. Fusion protein vaccine against pneumonia caused by Streptococcus pneumoniae [Text] / SUVOROV A. N., DUKHOVLINOV I. V., ORLOV A. I., BAIGUZIN E. Y.; applicant EPITOPE LTD [RF]. – No. 20150034192; applied on  21.01.15; publ. 02.04.15; priority 22.06.12, No. 2012126328 (RF). – 11 p.: Il.            
  99. Application 2013800377459 China, IPC 2006.01 A61K 39/02. Fusion protein vaccine against pneumonia caused by Streptococcus pneumoniae [Text] / SUVOROV A. N., DUKHOVLINOV I. V., ORLOV A. I., BAIGUZIN E. Y.; applicant EPITOPE LTD [RF]. – No. 104470538; applied on  15.01.15; publ. 25.03.15; priority 22.06.12, No. 2012126328 (RF). – 15 p.: Il.
  100. Application 2013139743 Russian Federation. IPC C07K 16/28. HUMANIZED MONOCLONAL ANTIBODY SPECIFIC to SYNDECAN-1 [Text] / Dukhovlinov I. V., Orlov A. I., Balazovsky M. B., Spector D. M., applicants Dukhovlinov I. V., Orlov A. I., Balazovsky M. B., Spector D. M. .  – No. 2013139743; applied on  26.08.2013; publ. 20.03.2015, Byul.  No. 8 . – 2 s.
  101. Pat. 2539913 Russian Federation, IPC 2006.01 A61K 39/00. Vaccine for the prevention and treatment of rotavirus infection, containing a fusion protein as an active agent (options) / Dukhovlinov I. V., Kadykov A. L., Simbirtsev A. S.; applicant and patent holder LLC “RD-biotech” (Russia). – No. 2013122473; applied on  15.05.2013, publ. 27.01.2015, Byul. No. 3. – 35 p.
  102. International application PCT/RU2014 / 000318, IPC 2006.01 A61K 39/00. Vaccine for the prevention and treatment of rotavirus infection, containing a fusion protein as an active agent (variants) / DUKHOVLINOV I. V., KADYKOV A. L., SIMBIRTSEV A. S.; applicant LLC “RD-BIOTECH” (Russia). – No. WO2014185817; applied on  14.05.2014, publ. 20.11.2014, priority 15.05.2013, № 2013122473 (RF). – 40 p.     
  103. Application 2013122473 Russian Federation, IPC 2006.01 A61K 39/00. Vaccine for the prevention and treatment of rotavirus infection, containing a fusion protein as an active agent (variants) / Dukhovlinov Ilya Vladimirovich (RU), Kadykov Alexander Leonidovich (RU), Simbirtsev Andrey Semenovich (RU); applicant LLC “RD-Biotech” (Russia). – No. 2013122473; applied on  15.05.2013, publ. 20.11.2014, Byul. No. 32. – 1 p.      
  104. Pat. 2531235 Russian Federation, IPC 2006.01 A61K 39/295. Polyvalent influenza vaccine based on fusion protein [Text] / Dukhovlinov I. V., Orlov A. I., Tsybalova L. M., Kiselev O. I. ; applicant and Pat.owner UBS LTD (Russia). – No. 2013107777; applied on  15.02.13; publ. 20.10.14, Byul. No. 29. – 21 p.: Il.
  105. International application PCT/RU2014/000096, IPC 2006.01 A61K 39/295. Polyvalent fusion protein vaccine against influenza [Text] / Dukhovlinov I. V., Orlov A. I., Tsybalova L. M., Kiselev O. I.; applicant UBS LTD (RF). – No. WO2014126510; applied on  14.02.14; publ. 21.08.14; priority 15.02.13, No. 2013107777 (RF). – 24 p.: Il.        
  106. Application 2013107777 Russian Federation, IPC 2006.01 A61K 39/295. Polyvalent vaccine against influenza based on fusion protein [Text] / Dukhovlinov I. V., Orlov A. I., Tsybalova L. M., Kiselev O. I.; applicant UBS LTD (Russia). – No. 2013107777; applied on  15.02.13; publ. 20.08.14, Byul. No. 23. – 1 s.
  107. Pat. 2510281 Russian Federation, IPC 2006.01 A61K 39/02. Vaccine against pneumonia caused by Streptococcus pneumoniae, based on a fusion protein [Text] / Suvorov A. N., Dukhovlinov I. V., Orlov A. I., Baiguzin E. Ya.; applicant and Pat.owner of Epitope LTD (Russia). – No. 2012126328; applied on  22.06.12; publ. 27.03.14, Byul. No. 9. – 15 p.: Il.  
  108. Application 2012136589 Russian Federation, IPC C12P 21/02. Recombinant human orexin A, used to extend the period of wakefulness, and the method of obtaining it [Text] / Dukhovlinov I. V., Orlov A. I., Fedorova E. A., Korneva E. A., Shainidze K. Z., Novikova N. S., Perekrest S. V.; applicant LLC “Orexal” ; applied on  21.08.12; publ. 27.02.14, Byul.  No. 6. – 2 s.
  109. International application PCT/RU2013 / 000525, IPC 2006.01 A61K 39/02. Fusion protein vaccine against pneumonia caused by Streptococcus pneumoniae [Text] / Suvorov A. N., Dukhovlinov I. V.; Orlov A. I., Baiguzin E. Y.; applicant EPITOPE LTD, NO. WO2013191591; applied on 21.06.2013; publ. 13.02.14; priority 22.06.12, No. 2012126328 (RF). – 19 p.
  110. Application 2012126328 Russian Federation, IPC 2006.01 A61K 39/02. Vaccine against pneumonia caused by Streptococcus pneumoniae, based on a fusion protein [Text] / Suvorov A. N., Dukhovlinov I. V., Orlov A. I., Baiguzin E. Ya.; applicant LLC “Epitope” (Russia). – No. 2012126328; applied on  22.06.12; publ. 27.12.13, Byul.  No. 36. – 1 s. 
  111. Application 201100196 Eurasia, IPC C07K 16/28, C07K 16/46. Humanized monoclonal antibody specific to CD20-antigen expressed by B-lymphocytes [Text] / Dukhovlinov I. V., Orlov A. I., Golyshev P. I.; applicant LLC “PHARMA GENE” ; applied on  02.12.10; publ. 30.03.12, Byul.  No. EAA21203. – 26 p.
  112. Application 201100203 Eurasia, IPC C07K 16/28, C12N 15/13, C12N 15/63. Monoclonal antibody specific to EGFR [Text] / Dukhovlinov I. V., Orlov A. I., Golyshev P. I.; applicant LLC “PHARMA GENE”; applied on  09.12.10; publ. 30.06.11, Byul.  No. EAA21103. – 28 p.
  113. Application 2010141064 Russian Federation, IPC A61K 31/00. Method of treatment of papillomavirus infections, implemented through the induction of interleukin-18 [Text] / Becker G. P. (RU), Dukhovlinov I. V. (RU), Nikonov B. A. (RU); applicant and Patent holder LLC “Alloferon” (RU). – No. 2010141064/15; applied on  07.10.2010, publ. 20.04.2012, Byul.  No. 11. – 1 p.    
  114. Pat. 2482866 Russian Federation, IPC A61K38/03, a61p31/22. Method of treatment of papillomavirus infections, implemented through the induction of interleukin-18 [Text] / Becker G. P., Dukhovlinov I. V., Nikonov B. A.; applicant and patentee LLC “Alloferon” (Russia). – No. 2010141064; applied on  07.10.2010; publ. 27.05.2013, Byul. No. 15. – 15 p.: Il.
  115. Pat. 2412946 Russian Federation, IPC C07K 16/10, C12P 21/00. A method for obtaining antibodies to HIV P17 protein [Text] / Al-Shekhadat R. I. (RU), Dukhovlinov I. V. (RU), Klimov N. A.( RU), Petrov A.V. (RU), Simbirtsev A. S. (RU), Kozlov A. P. (RU); applicant and Patentee FSUE research Institute of especially pure biopreparations FMBA (RU), non-State Research Institution “Biomedical Center” (RU). – No. 2009140376/10; applied on  03.11.2009, publ. 27.02.2011, Byul.  No. 6. – 5 p.: Il.        
  116. Application 2008149816 Russian Federation, IPC C07K 14/155, C07K 14/255, C12N 15/49.  Recombinant immunogen for immunization against human immunodeficiency virus P17 protein [ Text] / Kozlov A. P. (RU), Klimov N. A. (RU), Dukhovlinov I. V.( RU), Al-Shekhadat R. I. (RU); applicant FSUE GNII of especially pure biopreparations of FMBA (RU), non-State Research Institution “Biomedical Center” (RU). – No. 2008149816/13; applied on  18.12.2008, publ. 27.06.2010. – 1 p.
  117. Application 2008149821 Russian Federation, IPC C12N 15/62, C12N 15/12, C07K 14/195, C07K 19/00, A61K 39/02, A61K 39/04, A61P 31/06. Vaccine for the prevention and treatment of tuberculosis infection, recombinant fused protein FAE, recombinant plasmid DNA pFAE for its production [Text] / Kozlov A. P. (RU), Klimov N. A.( RU), Murashev B. V. (RU), Dukhovlinov I. V. (RU), Al-Shekhadat R. I. (RU), Chernyaeva E. N. (RU); applicant non-State Research Institution “Biomedical Center” (RU). – No. 2008149821/13; applied on  18.12.2008, publ. 27.06.2010. – 1 p.
  118. Pat. 2372941 Russian Federation, IPC A61K 48/00, C12N 15/17, C12N 15/12, C12N 15/85, C07H 21/04, A61P 5/00. A pharmaceutical composition for gene therapy of diseases requiring stimulation of regenerative processes, including damage of human tissues of various etiologies, based on a synthetic modified gene of insulin-like human growth factor of the first type (IGF-1, IGF-1) [Text] / Ivanov I. A. (RU); applicants and Pat.owners Dukhovlinov I. V. (RU), Ivanov I. A. (RU), LLC “Pharma Gen” (RU). – No. 2007124538; applied on  02.07.2007, publ. 20.11.2009, Byul.  No. 32. – 18 p: Il.    
  119. Application 2007124538 Russian Federation, IPC A61K 48/00. A pharmaceutical composition for gene therapy of diseases requiring stimulation of regenerative processes, including damage of human tissues of various etiologies, based on a synthetic modified gene of insulin-like human growth factor of the first type (IGF-1, IGF-1) [Text] / Ivanov I. A. (RU); applicants Dukhovlinov I. V. (RU), Ivanov I. A. (RU), LLC “Pharma Gen” (RU). – No. 2007124538/15; applied on  02.07.2007, publ. 10.01.2009, Byul.  No. 1. – 1 p.
  120. Pat. 2335540 Russian Federation, IPC C12N 15/00. Expression plasmid DNA pBMC-nef (A) – hum [Text] / Kozlov A. P. (RU), Klimov N. A. (RU), Murashev B. V. (RU), Dukhovlinov I. V. (RU), Astanina M. S. (RU), Masharsky A. E. (RU) ; applicant and patentee the state Research Institute of especially pure biopreparations FMBA (RU), ANO “Biomedical center” (RU). – No. 2006145771/13; applied on  25.12.2006, publ. 10.10.2008, Bulletin.  No. 28. – 8 p: Il.
  121. Application 2006145771 Russian Federation, IPC C12N 15/00. Stimulator of protein synthesis nef (A) – hum in eukaryotic cells [Text] / Kozlov A. P. (RU), Klimov N. A. (RU), Murashev B. V. (RU), Dukhovlinov I. V. (RU), Astanina M. S. (RU), Masharsky A. E. (RU); applicant and patentee of the state Research Institute of especially pure biopreparations FMBA (RU), ANO “biomedical center” (RU). – No. 2006145771/13; applied on  25.12.2006, publ. 27.06.2008, Byul. No. 18. – 1 p.     
  122. Pat. 2345138 Russian Federation, IPC C12N 15/63, C12N 15/48. Expression plasmid DNA p-VMS-gag(A)-hum for expression of HIV-1 protein P55 in eukaryotic cells [Text] / Kozlov A. P. (RU), Klimov N. A. (RU), Murashev B. V. (RU), Dukhovlinov I. V. (RU), Astanina M. S. (RU), Masharsky A. E. (RU) ; applicant and patentee The state research Institute of especially pure biopreparations of FMBA (RU), non-State Scientific and research institution “Biomedical center” (RU). – No. 2006145775/13; applied on  25.12.2006, publ. 27.01.2009, Byul.  No. 3. – 12 P: Il.
  123. Application 2006145775 Russian Federation, IPC C12N 15/63, C12N 15/48. Stimulator of P55 protein synthesis of HIV-1 in eukaryotic cells [Text] / Kozlov A. P. (RU), Klimov N. A.( RU), Murashev B. V. (RU), Dukhovlinov I. V. (RU), Astanina M. S. (RU), Masharsky A. E. (RU); applicant The state Research Institute of especially pure biopreparations FMBA (RU), non-State Research Institution “Biomedical Center” (RU). – No. 2006145775/13; applied on  25.12.2006, publ. 27.06.2008, Byul. no.18 – 1 p.
  124. Pat. 2355764 Russian Federation, IPC C12N 15/79, C12N 15/49. Recombinant plasmid DNA pBMC-RT(a)-hum for expression of reverse transcriptase protein of human immunodeficiency virus [Text] / Kozlov A. P. (RU), Klimov N. A. (RU), Murashev B. V. (RU), Dukhovlinov I. V. (RU), Astanina M. S. (RU), Masharsky A. E. (RU) ; applicant and patentee The state research Institute of especially pure biopreparations of FMBA (RU), non-State Scientific And research institution “Biomedical Center” (RU). – No. 2006145777/13; applied on  25.12.2006, publ. 20.05.2009, Byul.  No. 14. – 12 p.: Il.  20.05.2009, Byul.  No. 14. – 12 p.: Il.
  125. Application 2006145777 Russian Federation, IPC C12N 15/48. Stimulator of RT(A)-hum protein synthesis in eukaryotic cells [Text] / Kozlov A. P. (RU), Klimov N. A.(RU), Murashev B. V. (RU), Dukhovlinov I. V. (RU), Astanina M. S. (RU), Masharsky A. E. (RU); applicant The state research Institute of especially pure biopreparations of FMBA (RU), non-State Research Institution “Biomedical center” (RU). – No. 2006145777/13; applied on  25.12.2006, publ. 27.06.2008, Byul. No. 18. – 1 p.
  126. Pat. 2346044 Russian Federation, IPC C12N 15/00. Expression plasmid DNA pBMC-gp140(A) – hum [Text] / Kozlov A. P. (RU), Klimov N. A. (RU), Murashev B. V. (RU), Dukhovlinov I. V. (RU), Astanina M. S. (RU), Masharsky A. E. (RU) ; applicant and patentee The state research Institute of especially pure biopreparations of FMBA (RU), non-State Research Institution “Biomedical Center” (RU). – No. 2006145779/13; applied on  25.12.2006, publ. 10.02.2009, bul. no.4 – 15 p.
  127. Application 2006145779 Russian Federation, IPC C12N 15/00. Stimulator of protein synthesis Gp140 (A) – hum in eukaryotic cells [Text] / Kozlov A. P. (RU), Klimov N. A. (RU), Murashev B. V. (RU), Dukhovlinov I. V. (RU), Astanina M. S. (RU), Masharsky A. E. (RU); applicant of the state Research Institute of especially pure biopreparations FMBA (RU), ANO “Biomedical Center” (RU). – No. 2006145779/13; applied on  25.12.2006, publ. 27.06.2008, Byul.  No. 18. – 1 p.
  128. Pat. 2241752 Russian Federation, IPC C12N 15/48, C12N 15/63. Recombinant plasmid DNA PBMC-GAG(a)MOD for expression of human immunodeficiency virus gag protein in eukaryotic cells [Text] / Kozlov A. P. (RU), Klimov N. A. (RU), Masharsky A. E. (RU), Polyakova M. S. (RU), Romanovich A. E. (RU), Dukhovlinov I. V. (RU), Murashev B. V. (RU) ; applicant and patent Holder Autonomous non-profit organization “Biomedical Center” (RF). – No. 003116170; applied on  22.05.2003, publ. 10.12.2004, Byul.  No. 34. – 6 p.: Il.
  129. Application 2003116170 Russian Federation, IPC C12N 15/48, C12N 15/63. Recombinant plasmid DNA PBMC-GAG(a)MOD for expression of human immunodeficiency virus gag protein in eukaryotic cells [Text] / Kozlov A. P. (RU), Klimov N. A. (RU), Masharsky A. E. (RU), Polyakova M. S. (RU), Romanovich A. E. (RU), Dukhovlinov I. V. (RU), Murashev B. V. (RU) ; applicant Autonomous non-profit organization “Biomedical Center” (RF). – No. 2003116170/13; applied on  22.05.2003, publ. 10.12.2004. – 1 p.
  130. Pat. 2192277 Russian Federation, IPC A61K 39/12, A61K 39/112, C12N 1/21, C12N 1/21, C12R 1/42. Strain of bacteria Salmonella enteriditis E-23 BMC120 for immunization against human immunodeficiency virus [Text] / Kozlov A. P., Vorobiev A. A., Boychenko M. N., Klimov N. A., Murashev B. V., Masharsky A. E., Romanovich A. E., Dukhovlinov I. V., Dukhovlinova E. N.; applicant and patent Holder Autonomous non-profit organization “Biomedical Center” (RF). – No. 2001124265; applied on  24.08.2001, publ. 10.11.2002, Byul.  No. 31. – 6 p.: Il.
  131. Pat. 2192886 Russian Federation, IPC A61K 39/12, A61K 39/112, C12N 1/21, C12R 1/42. Salmonella typhimurium t-10 vmx160 bacterial strain for immunization against human immunodeficiency virus / Kozlov A. P., Vorobiev A. A., Boychenko M. N., Klimov N. A., Murashev B. V., Masharsky A. E., Romanovich A. E., Dukhovlinov I. V., Dukhovlinova E. N., Sandakhchiev L. S., Ilyichev A. A., Karpenko L. I., Nekrasova N. A.; applicant and Patentee Autonomous non-profit organization organization Biomedical Center, state scientific center of Virology and biotechnology “Vector” (Russia). – No. 20010124264; applied on  24.08.2001, publ. 20.11.2002, Byul.  No. 32. – 5 p.: Il.