Development | Vaccine | COVID-19 Vaccine Coronavirus Infection
COVID-19 Vaccine Coronavirus Infection Prevention and Treatment Vaccine
Our DNA vaccine contains sequences of all SARS-CoV-2 structural proteins (M, S, N, E) selected based on their T-cell immunogenicity. It primarily activates a T-cell immune response, which is crucial for combating viral infections.
Mechanism of action and advantages:
The vaccine's structure excludes the S-protein region (424-494AA) that directly interacts with the ACE2 cell surface receptor. This prevents the formation of cross-reactive antibodies against the human ACE2 receptor, thereby avoiding the autoimmune side effects characteristic of vaccines containing full-length S-protein or its ACE2-binding motif.
Our developed immunogen provides protection against both the original and mutant strains of coronavirus. In addition to the S-protein, the vaccine includes other structural coronavirus proteins (M, N, E), which are essential for developing robust immunity unaffected by viral mutations. This vaccine is suitable for both prevention and treatment of novel coronavirus infections.
COVID-19 Vaccine Coronavirus Infection Prevention and Treatment Vaccine
Our DNA vaccine contains sequences of all SARS-CoV-2 structural proteins (M, S, N, E) selected based on their T-cell immunogenicity. It primarily activates a T-cell immune response, which is crucial for combating viral infections.
Mechanism of action and advantages:
The vaccine's structure excludes the S-protein region (424-494AA) that directly interacts with the ACE2 cell surface receptor. This prevents the formation of cross-reactive antibodies against the human ACE2 receptor, thereby avoiding the autoimmune side effects characteristic of vaccines containing full-length S-protein or its ACE2-binding motif.
Our developed immunogen provides protection against both the original and mutant strains of coronavirus. In addition to the S-protein, the vaccine includes other structural coronavirus proteins (M, N, E), which are essential for developing robust immunity unaffected by viral mutations. This vaccine is suitable for both prevention and treatment of novel coronavirus infections.
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