Recombinant proteins | Insulin-like Growth Factor 1 | Cartilage Regeneration Agent
Cartilage Regeneration Agent
Highly specific protein and DNA molecules have been developed to provide:

Targeted action – selective impact on the cartilage matrix.
Safety and cost-effectiveness – both in production and application.
A modified version of this hybrid protein has also been developed for oral delivery.

The components of the proposed cartilage regeneration agent may include the aforementioned proteins or plasmid DNA encoding such hybrid proteins.

Key advantages of the development:

Mechanism of action:

• Activation of satellite cells → increased number of muscle nuclei
• Enhanced protein synthesis
• Suppression of myostatin (a muscle growth-limiting protein)
• Increased amino acid uptake by muscle cells

The components of the hybrid protein are connected by flexible linkers, enabling each protein component to function effectively and promote efficient cartilage tissue regeneration.

Clinical effects of the development include:

• Accelerated cartilage tissue regeneration
• Selective action – targeting only damaged areas
• Dual effect: local accumulation in the cartilage matrix and stimulation of necessary cell growth

AAdvantages over traditional methods:
AApplication prospects
The technology is particularly relevant for:

• Treating osteoarthritis and sports injuries
• Post-joint surgery rehabilitation
• Preventing degenerative cartilage changes

Conclusion: The development opens new possibilities in regenerative medicine, combining high efficacy with safety and user-friendly application.