SUPEROXIDE DISMUTASE (SOD)

SUPEROXIDE DISMUTASE

the Eurasian application for invention No. 201650120 stated 01.12.2016

Superoxide dismutases (SOD) are a group of antioxidant enzymes that protect the body from constantly forming highly toxic oxygen radicals. SOD plays a crucial role in the antioxidant protection of almost all cells, one way or another in contact with oxygen.

Extracellular SOD (ECSOD) plays an important role in the pathophysiology of various diseases and conditions associated with oxidative stress, including high blood pressure, heart failure, ischemic and reperfusion injury, increased platelet aggregation, and atherosclerosis. These diseases are the leading cause of death in the world.

Given the potential of ECSOD in protection against such diseases, which is difficult to overestimate, obtaining this active enzyme in large quantities is an urgent task.

A strain-producer of ECSOD protein based on E. coli cells and a method for obtaining this active protein in large quantities have been developed